Document Detail


An ultrastructural study on arrhythmogenic right ventricular dysplasia with special reference to lipid droplets.
MedLine Citation:
PMID:  2093714     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myocardial tissues in arrhythmogenic-right ventricular dysplasia (ARVD), which were surgically resected from the site of origin of ventricular tachycardia (VT), were investigated optically and electron-microscopically. The site of origin was found to be occupied by an abundance of adipose cells. In the marginal zone, lipid droplets were obviously increased in count in the cytoplasm of both myocytes and blood capillary-endothelium, rather more than in distant areas. Lipid droplets in the endothelial cells also occurred at a higher frequency in the ARVD group than in any other myocardial disease showing VT. A mechanism which increases lipid droplets in the cytoplasm of cardiomyocytes and endothelial cells operates at the VT origin site in ARVD. Intraendothelial lipids may be an important diagnostic finding in the histology of ARVD.
Authors:
F Masani; Y Aizawa; T Izumi; A Shibata
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart and vessels. Supplement     Volume:  5     ISSN:  0935-736X     ISO Abbreviation:  Heart Vessels Suppl     Publication Date:  1990  
Date Detail:
Created Date:  1991-06-21     Completed Date:  1991-06-21     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  8810802     Medline TA:  Heart Vessels Suppl     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  55-8     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Niigata University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arrhythmias, Cardiac / pathology*
Cytoplasm / ultrastructure
Endothelium, Vascular / ultrastructure
Heart Ventricles / ultrastructure*
Humans
Lipids*
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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