| The type specimen (LB1) of Homo floresiensis did not have Laron syndrome. | |
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MedLine Citation:
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PMID: 19294744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The type specimen (LB1) of Homo floresiensis has been hypothesized to be a pathological human afflicted with Laron Syndrome (LS), a type of primary growth hormone insensitivity (Hershkovitz et al.: Am J Phys Anthropol 134 [2007] 198-208). Comparing measurements, photographs and three-dimensional, computed-tomography reconstructions of LB1 with data and diagnoses from the literature on LS, we critically evaluate numerous skull and postcranial traits that Hershkovitz et al. identified as being shared by LB1 and patients with LS. The statements regarding most of these traits are new to the clinical literature and lack quantitative support. LB1 and patients with LS differ markedly in the size and shape of the cranium; thickness and pneumatization of cranial bones; morphology of the face, mandible, teeth, and chin; form of the shoulder, wrist, and pelvis; and general body proportions including relative foot size. Claims that patients with LS are similar to LB1 in displaying protracted scapulae, short clavicles, low degrees of humeral torsion, flaring ilia, and curved tibiae are not supported by data or corroborating images. Some points of similarity (e.g., femoral neck-shaft angle, femoral bicondylar angle, and estimated stature) can be found in other hominins, and cannot be considered diagnostic. From our review and analysis, we conclude that LB1 did not suffer from LS. |
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Authors:
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Dean Falk; Charles Hildebolt; Kirk Smith; William Jungers; Susan Larson; Michael Morwood; Thomas Sutikna; Jatmiko; E Wahyu Saptomo; Fred Prior |
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Publication Detail:
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Type: Comment; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of physical anthropology Volume: 140 ISSN: 1096-8644 ISO Abbreviation: Am. J. Phys. Anthropol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-01 Completed Date: 2009-11-17 Revised Date: 2010-10-20 |
Medline Journal Info:
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Nlm Unique ID: 0400654 Medline TA: Am J Phys Anthropol Country: United States |
Other Details:
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Languages: eng Pagination: 52-63 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Wiley-Liss, Inc. |
Affiliation:
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Department of Anthropology, Florida State University, Tallahassee, FL 32306-7772, USA. dfalk@fsu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Size* Female Fossils* Hominidae* Humans Imaging, Three-Dimensional Laron Syndrome / pathology*, radiography Male Pelvis / pathology, radiography Skull / pathology*, radiography Tomography, X-Ray Computed |
| Comments/Corrections | |
Comment On:
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Am J Phys Anthropol. 2007 Oct;134(2):198-208
[PMID:
17596857
]
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Comment In:
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Am J Phys Anthropol. 2010 Nov;143(3):331-4; discussion 355-42
[PMID:
20809509
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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