| The triplet genetic code had a doublet predecessor. | |
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MedLine Citation:
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PMID: 15748913 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and anticodons GNN. Evidence for this scenario is presented based on the properties of aminoacyl-tRNA synthetases, amino acids and nucleotide bases. |
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Authors:
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Apoorva Patel |
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Publication Detail:
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Type: Journal Article Date: 2004-12-29 |
Journal Detail:
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Title: Journal of theoretical biology Volume: 233 ISSN: 0022-5193 ISO Abbreviation: J. Theor. Biol. Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-03-07 Completed Date: 2005-06-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376342 Medline TA: J Theor Biol Country: England |
Other Details:
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Languages: eng Pagination: 527-32 Citation Subset: IM |
Affiliation:
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Centre for High Energy Physics and Supercomputer Education and Research Centre, Indian Institute of Science, Bangalore 560012, India. adpatel@cts.iisc.ernet.in |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Motifs Amino Acyl-tRNA Synthetases / genetics Animals Base Composition Biogenesis Codon Conserved Sequence Evolution, Molecular* Genetic Code Models, Genetic* Trinucleotide Repeats* |
| Chemical | |
Reg. No./Substance:
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0/Codon; EC 6.1.1.-/Amino Acyl-tRNA Synthetases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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