Document Detail

The triglyceride issue: a view from Framingham.
MedLine Citation:
PMID:  3739899     Owner:  NLM     Status:  MEDLINE    
Triglycerides make up the overwhelming proportion of dietary fat consumed in the United States and other industrialized nations. Triglyceride elevation is directly associated with relative weight and age in both sexes, oral contraceptive use in women, and the development of diabetes mellitus. Triglyceride elevations are a highly significant independent risk factor for coronary heart disease (CHD) in women. They appear to be important in men with low high-density lipoprotein (HDL) cholesterol (less than 40 ml/dl). Dangerously high levels of triglyceride are associated with a high total cholesterol/HDL cholesterol ratio, which is an excellent indicator of CHD risk in both sexes. Individuals with elevated triglycerides should be considered at risk for CHD unless the total cholesterol/HDL cholesterol ratio is under 3.5. In practice, however, only about 10% of individuals with elevated triglycerides prove to have such low total cholesterol/HDL cholesterol ratios.
W P Castelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  112     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  432-7     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Apolipoproteins / metabolism
Body Weight
Child, Preschool
Cholesterol / blood
Cholesterol, HDL / blood
Chylomicrons / metabolism
Contraceptives, Oral
Coronary Disease / blood,  epidemiology*
Diabetes Mellitus / blood
Dietary Fats / administration & dosage*
Intestinal Absorption
Middle Aged
Triglycerides / administration & dosage*,  blood
United States
Reg. No./Substance:
0/Apolipoproteins; 0/Cholesterol, HDL; 0/Chylomicrons; 0/Contraceptives, Oral; 0/Dietary Fats; 0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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