Document Detail


The treatment of sacral giant-cell tumours by serial arterial embolisation.
MedLine Citation:
PMID:  12211682     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Giant-cell tumours of the sacrum are difficult to treat. Surgery carries a high risk of morbidity, local recurrence and mortality. Radiation is effective in some patients, but has a risk of malignant change. We evaluated the effectiveness of serial arterial embolisation as an alternative to surgery. Five patients with giant-cell tumours of the sacrum which had been primarily treated by serial embolisation were retrospectively reviewed for changes in the size of the tumour. In four the symptoms resolved with full return of function and arrest in the growth of the tumour. They remained free from growth, recurrence, or metastases at follow-up (4 to 17 years). One patient died from metastatic disease within 18 months of the initial diagnosis.
Authors:
R D Lackman; L D Khoury; A Esmail; R Donthineni-Rao
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of bone and joint surgery. British volume     Volume:  84     ISSN:  0301-620X     ISO Abbreviation:  J Bone Joint Surg Br     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-09-04     Completed Date:  2002-09-27     Revised Date:  2010-11-10    
Medline Journal Info:
Nlm Unique ID:  0375355     Medline TA:  J Bone Joint Surg Br     Country:  England    
Other Details:
Languages:  eng     Pagination:  873-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Orthopaedic Surgery, The Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angiography
Bone Neoplasms / therapy*
Embolization, Therapeutic / methods*
Female
Giant Cell Tumor of Bone / therapy*
Humans
Male
Retrospective Studies
Sacrum
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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