Document Detail

The treatment of refractory pneumothorax in diffuse panbronchiolitis by intravenous administration of coagulation factor XIII concentrate.
MedLine Citation:
PMID:  16641533     Owner:  NLM     Status:  MEDLINE    
This case report presents a patient with advanced diffuse panbronchiolitis accompanied by chronic respiratory failure, marked cachexia, and refractory spontaneous pneumothorax. Because instillation of a pleurodesis agent and thoracoscopy were considered highly risky and invasive, we instead treated the patient with intravenous administration of a coagulation factor XIII concentrate, and the pneumothorax resolved. This case suggests refractory pneumothorax in a restrictive ventilatory disorder can be effectively treated with noninvasive intravenous administration of coagulation factor XIII concentrate.
Akira Murata; Ayumi Kouno; Kazuo Yamamoto; Hiroko Yoshioka; Kozui Kida; Shoji Kudoh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of Nippon Medical School = Nippon Ika Daigaku zasshi     Volume:  73     ISSN:  1345-4676     ISO Abbreviation:  J Nippon Med Sch     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-27     Completed Date:  2006-07-21     Revised Date:  2012-09-25    
Medline Journal Info:
Nlm Unique ID:  100935589     Medline TA:  J Nippon Med Sch     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  89-92     Citation Subset:  IM    
Department of Pulmonary Medicine, Infection and Oncology, Nippon Medical School, Sendagi, Tokyo, Japan.
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MeSH Terms
Bronchiolitis / complications*
Factor XIII / administration & dosage,  therapeutic use*
Injections, Intravenous
Middle Aged
Pneumothorax / drug therapy*
Reg. No./Substance:
9013-56-3/Factor XIII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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