| The treatment of pelvic soft tissue radiation necrosis with hyperbaric oxygen. | |
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MedLine Citation:
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PMID: 1497044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to examine the therapeutic effects of hyperbaric oxygen on radiation-induced soft tissue necrosis in patients who previously received treatment for a gynecologic malignancy. STUDY DESIGN: Fourteen patients whose necrotic wounds failed to heal after 3 months of conservative therapy were enrolled in a prospective observational study. Outcome of hyperbaric oxygen treatment was measured by resolution of necrosis. RESULTS: Fourteen patients underwent 15 courses of hyperbaric oxygen treatments. All those with radiation necrosis of the vagina alone or in association with rectovaginal fistula had complete resolution of necrosis with hyperbaric oxygen. Only one treatment failure occurred. CONCLUSION: Hyperbaric oxygen is a safe, effective, and well-tolerated treatment for radiation-induced soft tissue necrosis. |
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Authors:
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J A Williams; D Clarke; W A Dennis; E J Dennis; S T Smith |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 167 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-09-10 Completed Date: 1992-09-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 412-5; discussion 415-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of South Carolina, Columbia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Evaluation Studies as Topic Female Genital Neoplasms, Female / radiotherapy* Humans Hyperbaric Oxygenation* Middle Aged Necrosis Pelvis / pathology, radiation effects* Radiation Injuries / therapy* Rectovaginal Fistula / therapy Vagina / radiation effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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