Document Detail

The treatment of donor sites with cultured epithelial grafts.
MedLine Citation:
PMID:  1993229     Owner:  NLM     Status:  MEDLINE    
In a significant number of elderly patients, the healing of split skin donor sites can be delayed. The cultured allogenic epithelial graft (CAG) has been reported to heal leg ulcers. The mechanism of action may be to improve the healing environment and thus stimulate the host skin cells. A clinical trial was undertaken to compare the healing rate of the donor sites of elderly patients using CAGs and two commercially available dressings. Compared to Jelonet, CAGs (p = 0.008) and OpSite (p = 0.013) significantly reduced the number of patients with delayed healing. There was no significant difference between CAGs and the occlusive dressing, OpSite.
A Blight; M F Fatah; D D Datubo-Brown; E M Mountford; I M Cheshire
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  British journal of plastic surgery     Volume:  44     ISSN:  0007-1226     ISO Abbreviation:  Br J Plast Surg     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-03-15     Completed Date:  1991-03-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984714R     Medline TA:  Br J Plast Surg     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  12-4     Citation Subset:  IM    
Skin Culture Laboratory, Birmingham Accident Hospital.
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MeSH Terms
Aged, 80 and over
Biological Dressings*
Cells, Cultured
Epithelium / transplantation*
Middle Aged
Skin Transplantation*
Wound Healing / physiology*
Reg. No./Substance:
0/Opsiture; 0/Polyurethanes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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