Document Detail

The treatment of actinic keratoses.
MedLine Citation:
PMID:  10607354     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Actinic keratoses are epidermal tumors that can develop into invasive squamous cell carcinoma. Recently, some Medicare carriers have limited reimbursement for destruction of actinic keratoses. OBJECTIVE: We review treatments for actinic keratoses and the rationale for their use. METHODS: Computerized literature searches were performed in MEDLINE. The search terms were "actinic keratoses" and "solar keratosis." Information from these searches was combined with considerable personal experience for the body of this work. RESULTS: Many effective treatments for actinic keratoses exist. Cryosurgery and curettage are the most commonly used treatments. Cryosurgery is considered the standard of care for treatment of actinic keratoses. Topical 5-fluorouracil is used in 3. 6% of cases and is rarely used alone on the first patient visit. Many other effective, less commonly used treatments are available. CONCLUSION: A physician should select the best treatment by considering features of the lesion(s) and the patient being treated. All actinic keratoses cannot be treated in the same manner. The failure to treat actinic keratoses may have serious consequences for the patient.
S M Dinehart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  42     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-01-28     Completed Date:  2000-01-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  25-8     Citation Subset:  IM    
Department of Dermatology, Department of Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock 72205, USA.
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MeSH Terms
Administration, Topical
Antimetabolites / administration & dosage,  therapeutic use
Fluorouracil / administration & dosage,  therapeutic use
Keratosis / therapy*
Photosensitivity Disorders / therapy*
Reg. No./Substance:
0/Antimetabolites; 51-21-8/Fluorouracil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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