Document Detail

The treatment of Pseudomonas keratoscleritis after pterygium excision.
MedLine Citation:
PMID:  10487438     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the effect of intensive topical and intravenous antibiotics plus oral prednisolone and surgical debridement in Pseudomonas keratoscleritis after pterygium excision. METHODS: We describe three cases of P. aeruginosa-induced keratoscleritis occurring 10 days to 18 months after uncomplicated pterygium excision. Treatment included early conjunctival debridement, topical and intravenous antibiotics, and low-dosage oral prednisolone. RESULTS: All three patients responded to the combined therapy. Microorganisms were eliminated, and ulcers were healed within 8 weeks. Treatment was not extended beyond that, and infection did not recur. No evisceration was required. The patients' best corrected visual acuities are 20/200, 20/400, and 20/120, respectively. CONCLUSION: Early diagnosis and prompt, intensive medical and surgical treatment may save a patient's vision and forestall evisceration.
S C Huang; H C Lai; I C Lai
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cornea     Volume:  18     ISSN:  0277-3740     ISO Abbreviation:  Cornea     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-13     Completed Date:  1999-10-13     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  608-11     Citation Subset:  IM    
Department of Ophthalmology, Chang-Gung Memorial Hospital, Chang-Gung University, Taipei, Taiwan.
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MeSH Terms
Administration, Oral
Anti-Bacterial Agents
Corneal Ulcer / microbiology,  therapy*
Drug Therapy, Combination / therapeutic use
Eye Infections / microbiology,  therapy*
Injections, Intravenous
Middle Aged
Postoperative Complications / microbiology,  therapy*
Prednisolone / therapeutic use
Pseudomonas Infections / microbiology,  therapy*
Pseudomonas aeruginosa / isolation & purification
Pterygium / surgery*
Scleritis / microbiology,  therapy*
Reg. No./Substance:
0/Anti-Bacterial Agents; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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