| Is transurethral biopsy of the bladder necessary after 3 months to evaluate response to bacillus Calmette-Guerin therapy? | |
| | |
MedLine Citation:
|
PMID: 10458348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: We assessed the need for transurethral biopsy of the bladder at the 3-month evaluation in patients who have received intravesical bacillus Calmette-Guerin (BCG). MATERIALS AND METHODS: A total of 81 patients collectively received 83, 6-week courses of BCG between 1995 and 1997, and underwent transurethral bladder biopsies 3 months after initiation of immunotherapy. The pretreatment and posttreatment bladder biopsy results, urinary cytology and posttreatment cystoscopic findings were correlated. RESULTS: Transitional cell carcinoma was demonstrated in 5 of 11 patients with erythematous bladder mucosa and a positive cytology compared to none of 37 with an erythematous lesion and a negative cytology. Of 12 patients with a papillary lesion on cystoscopy and a positive biopsy 10 had a negative cytology, and only 1 of 13 patients with a negative cystoscopy had a positive biopsy. CONCLUSIONS: Bladder biopsy is not necessary in patients 3 months after receiving BCG who have a normal office cystoscopy or an erythematous bladder and normal urine cytology. |
| | |
Authors:
|
G Dalbagni; T Rechtschaffen; H W Herr |
Related Documents
:
|
19519608 - Extra-anogenital bilharziasis cutanea tarda revisited. 15164258 - Tuberculous vertebral osteomyelitis in the new millennium: still a diagnostic and thera... 9093588 - 'localized amyloidosis': 123i-labelled sap component scintigraphy and labial salivary g... 1944988 - Breast-conserving therapy for invasive carcinoma: diagnosis of local recurrence. 1894168 - Manometric characterization of rectal dysfunction following radical hysterectomy. 19372358 - Surface anatomy as a guide to vertebral level for thoracic epidural placement. |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: The Journal of urology Volume: 162 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1999 Sep |
Date Detail:
|
Created Date: 1999-09-23 Completed Date: 1999-09-23 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 708-9 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adjuvants, Immunologic
/
therapeutic use* Adult Aged Aged, 80 and over BCG Vaccine / therapeutic use* Biopsy / statistics & numerical data* Carcinoma, Transitional Cell / drug therapy*, pathology* Female Humans Male Middle Aged Time Factors Urethra Urinary Bladder Neoplasms / drug therapy*, pathology* |
| Chemical | |
Reg. No./Substance:
|
0/Adjuvants, Immunologic; 0/BCG Vaccine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Recurrence and progression in low grade papillary urothelial tumors.
Next Document: A stage specific approach to tumor surveillance after radical cystectomy for transitional cell carci...