Document Detail

The transmyocardial laser revascularization international registry report.
MedLine Citation:
PMID:  10075139     Owner:  NLM     Status:  MEDLINE    
AIMS: This report aimed to provide an analysis of the data submitted from Europe and Asia on transmyocardial laser revascularization. METHODS AND RESULTS: Prospective data was recorded on 967 patients with intractable angina not amenable to conventional revascularization in 21 European and Asian centres performing transmyocardial laser revascularization using the PLC Medical Systems CO2 laser. Patient characteristics, operative details and early complications following transmyocardial laser revascularization were recorded. The in-hospital death rate was 9.7% (95% confidence interval 7.8% to 11.6%). Other early complications were consistent with similar cardiothoracic surgical procedures. There was a decrease of two or more Canadian Cardiovascular Score angina classes in 47.3%, 45.4% and 34.0% of survivors at 3, 6 and 12 months follow-up, respectively (P=0.001 for each). Treadmill exercise time increased by 42 s at 3 months (P=0.008), 1 min 43 s at 6 months (P<0.001) and 1 min 50 s at 12 months (P<0.001) against pre-operative times of 6 min. CONCLUSION: Uncontrolled registry data suggest that transmyocardial laser revascularization may lead to a decrease in angina and improved exercise tolerance. It does, however, have a risk of peri-operative morbidity and mortality. Definitive results from randomized controlled trials are awaited.
S M Burns; L D Sharples; S Tait; N Caine; J Wallwork; P M Schofield
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European heart journal     Volume:  20     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-05-04     Completed Date:  1999-05-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  31-7     Citation Subset:  IM    
Department of Cardiology, Papworth Hospital NHS Trust, Papworth Everard, Cambridge UK.
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MeSH Terms
Aged, 80 and over
Angina Pectoris / diagnosis,  mortality,  surgery*
Asia / epidemiology
Europe / epidemiology
Exercise Test
Follow-Up Studies
Hospital Mortality
Laser Therapy* / mortality,  statistics & numerical data
Middle Aged
Myocardial Revascularization* / methods,  mortality,  statistics & numerical data
Postoperative Complications / mortality
Prospective Studies
Registries / statistics & numerical data*
Survival Rate
Treatment Outcome
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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