Document Detail


A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration.
MedLine Citation:
PMID:  3875568     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Four of 30 patients with a diagnosis of B-CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13.1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.
Authors:
Y Ueshima; M L Bird; J W Vardiman; J D Rowley
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  36     ISSN:  0020-7136     ISO Abbreviation:  Int. J. Cancer     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-10-17     Completed Date:  1985-10-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  287-90     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
B-Lymphocytes
Bone Marrow Cells
Chromosome Aberrations*
Chromosomes, Human, 13-15*
Chromosomes, Human, 19-20*
Humans
Karyotyping
Leukemia, Lymphoid / genetics*
Male
Translocation, Genetic*
Grant Support
ID/Acronym/Agency:
CA 19266/CA/NCI NIH HHS; T 32-GM7190/GM/NIGMS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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