Document Detail


A translocation between 3q21 and 12q24 in a patient with minimally differentiated acute myeloid leukemia (AML-M0).
MedLine Citation:
PMID:  9283587     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Only a small number of reports have described the cytogenetic analysis of minimally differentiated acute myeloid leukemia (AML, M0). We performed a cytogenetic analysis on a patient with AML (M0) with a normal platelet count. It revealed a chromosomal translocation between chromosome bands 3q21 and 12q24. 3q. Abnormalities in AML are known to be associated with normal or elevated platelet counts. 3q21 and 12q24 are common translocation sites in AML patients, but this is the first report of translocation t(3;12)(q21;q24) in an AML patient.
Authors:
N Yamagata; C Shimazaki; T Kikuta; H Hirai; T Sumikuma; Y Sudo; E Ashihara; H Goto; T Inaba; N Fujita; M Nakagawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  97     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-09-17     Completed Date:  1997-09-17     Revised Date:  2009-10-30    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  90-3     Citation Subset:  IM    
Affiliation:
Second Department of Medicine, Kyoto Prefectural University of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Cell Differentiation
Chromosome Aberrations*
Chromosome Banding
Chromosome Disorders
Chromosome Mapping
Chromosomes, Human, Pair 12*
Chromosomes, Human, Pair 3*
Humans
Leukemia, Myeloid / genetics*,  pathology
Male
Middle Aged
Translocation, Genetic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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