Document Detail


The toxicity and oxidative stress of TiO(2) nanoparticles in marine abalone (Haliotis diversicolor supertexta).
MedLine Citation:
PMID:  21492882     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The increasing use of nanotechnology highlights the need to understand and clarify the environmental impacts of nanomaterials. In this study, the acute toxicity and oxidative stress of titanium dioxide nanoparticles (nTiO(2)) in mature marine abalone (Haliotis diversicolor supertexta) were assessed. No acute effect was found in any of the treatment groups with nTiO(2) concentration gradients ranging from 0.1 to 10mg/L. However, the activity of an antioxidant enzyme superoxide dismutase (SOD) significantly increased in the group that was exposed to 1.0mg/L nTiO(2). The content of a non-enzymatic antioxidant, glutathione (GSH), significantly decreased in the groups with an nTiO(2) concentration ⩾1.0mg/L. The level of lipid peroxidation (LPO) was found to increase as the nTiO(2) dose increased. Furthermore, NO was produced in excess in abalone. These results demonstrated that, although nTiO(2) is not acutely toxic to abalone, it does exert oxidative stress on abalone.
Authors:
Xiaoshan Zhu; Jin Zhou; Zhonghua Cai
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-12
Journal Detail:
Title:  Marine pollution bulletin     Volume:  -     ISSN:  1879-3363     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0260231     Medline TA:  Mar Pollut Bull     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Marine Biology Laboratory, Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.
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