Document Detail


The toxicity evaluation of nano-trititanate with bactericidal properties in vitro.
MedLine Citation:
PMID:  21554015     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Three forms of nano-trititanate (H(2)Ti(3)O(7) nanomaterial) were prepared by a hydrothermal method to replace nano-TiO(2) for sterilizing the environment. The bactericidal capabilities of these nano-trititanates were observed to be more significant compared to nano-TiO(2) both with and without exposure to UV light. For the future commercial applications of those nano-trititanates, we investigated their cytotoxicity and genotoxicity to HEp-2 cells. As data in our study shows, nanoplate, one of the nano-trititanates, possesses the lowest toxicity to HEp-2 cells. The results indicated that the shape and length of the material only affect the toxicity of nano-trititanate but not its bactericidal effect. Thus, through manipulating the shape or length of nano-trititanate, we may obtain a more powerful bactericidal reagent with lower toxicity to the human body.
Authors:
Rong Pan; Yang Liu; Wei Chen; Graham Dawson; Xin Wang; Yan Li; Bing Dong; Yimin Zhu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-9
Journal Detail:
Title:  Nanotoxicology     Volume:  -     ISSN:  1743-5404     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101233132     Medline TA:  Nanotoxicology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Nanobiomedicine Division, Suzhou Institute of Nano-Tech and Nano-Bionics , Chinese Academy of Sciences, Suzhou, Jiangsu 215123, P. R . China.
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