| The toxic effects of triorganotin(IV) compounds on the culicine mosquito, Aedes aegypti (L). | |
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MedLine Citation:
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PMID: 6204424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The structure-activity relationships of 25 triorganotin(IV) compounds were studied using the 4th instar A. aegypti larvae of the susceptible Liverpool Red-eye strain. The LC50 values of these compounds were compared with those of Malathion, DDT and Temephos. Maximal activities were obtained with tritolyltin chloride and its complexes with triphenyl-phosphine oxide and pyridine N-oxide, dimethyloctyltin- and diethyloctyltin acetates and tributyltin sucrose phthalate. A limited number of the triorganotin compounds was also tested with observed high activity against the 4th instar larvae of a local DDT-tolerant strain and against the 2nd instar larvae and adults of the susceptible strain. Delayed effect studies with both 2nd and 4th instar larvae showed high post-treatment mortality for the latter and, among the range of active compounds, the methyl- and aryltin compounds, in particular, were also found to exhibit high residual activities (100% kill) in laboratory tests conducted up to 10 weeks. |
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Authors:
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V G Kumar Das; L Y Kuan; K I Sudderuddin; C K Chang; V Thomas; C K Yap; M K Lo; G C Ong; W K Ng; Y Hoi-Sen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Toxicology Volume: 32 ISSN: 0300-483X ISO Abbreviation: Toxicology Publication Date: 1984 Jul |
Date Detail:
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Created Date: 1984-08-13 Completed Date: 1984-08-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0361055 Medline TA: Toxicology Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 57-66 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aedes
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drug effects* Animals DDT / toxicity Female Larva / drug effects Lethal Dose 50 Malathion / toxicity Organotin Compounds / toxicity* Structure-Activity Relationship Temefos / toxicity |
| Chemical | |
Reg. No./Substance:
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0/Organotin Compounds; 121-75-5/Malathion; 3383-96-8/Temefos; 50-29-3/DDT |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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