| PET/CT today and tomorrow in veterinary cancer diagnosis and monitoring: fundamentals, early results and future perspectives. | |
| | |
MedLine Citation:
|
PMID: 20691025 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Functional imaging using positron emission tomography (PET) plays an important role in the diagnosis, staging, image-guided treatment planning and monitoring of malignant diseases. PET imaging complements conventional anatomical imaging such as computed tomography (CT) and magnetic resonance imaging (MRI). The strength of CT scanning lies in its high spatial resolution, allowing for anatomical characterization of disease. PET imaging, however, moves beyond anatomy and characterizes tissue based on functions such as metabolic rate. Combined PET/CT scanners were introduced commercially in 2001 and a number of technological advancements have since occurred. Radiolabelled tracers such as (18)F-fluorodeoxyglucose (FDG) and (18)F-fluorothymidine (FLT) allow visualization of various metabolic processes within cancer cells. Many studies in human oncology evaluating the utility of PET/CT have demonstrated clinical benefits. Few veterinary studies have been performed, but initial studies show promise for improved detection of malignancy, more thorough staging of canine cancer and determination of early response and disease recrudescence. |
| | |
Authors:
|
J Lawrence; E Rohren; J Provenzale |
Related Documents
:
|
19184245 - The early use of pet-ct alters the management of patients with esophageal cancer. 18088235 - The promise of pet in clinical management and as a sensitive test for drug cytotoxicity... 16777405 - The role of anatomic and functional staging in myeloma: description of durie/salmon plu... 10369275 - Uses and limitations of fdg positron emission tomography in patients with head and neck... 10694845 - Contrast-enhanced magnetic resonance activity in relapsing remitting multiple sclerosis... 17414885 - 68ga-dotatate pet in neuroectodermal tumours: first experience. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Veterinary and comparative oncology Volume: 8 ISSN: 1476-5829 ISO Abbreviation: Vet Comp Oncol Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-09 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101185242 Medline TA: Vet Comp Oncol Country: England |
Other Details:
|
Languages: eng Pagination: 163-87 Citation Subset: IM |
Affiliation:
|
Department of Small Animal Medicine and Surgery, University of Georgia, College of Veterinary Medicine, Athens, GA 30602, USA. lawrence@uga.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cat Diseases / diagnosis, radionuclide imaging* Cats Dog Diseases / diagnosis, radionuclide imaging* Dogs Fluorodeoxyglucose F18 / diagnostic use Humans Neoplasm Staging Neoplasms / diagnosis, radionuclide imaging, veterinary* Positron-Emission Tomography / methods, trends, veterinary* Radiopharmaceuticals / diagnostic use Tomography Scanners, X-Ray Computed / trends, veterinary |
| Chemical | |
Reg. No./Substance:
|
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance...
Next Document: Doxorubicin and cyclophosphamide for the treatment of canine lymphoma: a randomized, placebo-control...