Document Detail

The timing of histologic changes in liver lacerations.
MedLine Citation:
PMID:  18725772     Owner:  NLM     Status:  MEDLINE    
Microscopic examination was performed on 55 cases of traumatic liver lacerations incurred from fatal motor vehicle accidents. None of the deaths was due to the liver injury. In 38 of 55 cases, the decedent was pronounced dead at the scene. Microscopic examination of the liver lacerations in these 38 cases revealed no histologic changes related to the trauma. In 17 of 55 cases, the decedent was transported to the emergency room (ER) with a "survival time" (from Emergency Medical Service arrival to the time of pronouncement) of 15 minutes to 7 hours and 10 minutes. Nine of these 17 had vital signs at the scene. Five of the 17 had neutrophilic infiltration and hepatocyte necrosis at the site of the laceration. Four of these had vitals signs at the scene. Survival time of the 5 patients with a vital reaction at their liver injury ranged from 51 minutes to 7 hours and 10 minutes.
R E Kohlmeier; V J M Dimaio; F Sharkey; E A Rouse; K E Reeves
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  29     ISSN:  1533-404X     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-26     Completed Date:  2008-10-21     Revised Date:  2011-02-02    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  206-7     Citation Subset:  IM    
Bexar County Forensic Science Center, San Antonio, Texas; daggerThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
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MeSH Terms
Accidents, Traffic
Fatty Liver / pathology
Forensic Pathology
Hepatocytes / pathology
Lacerations / pathology*
Liver / injuries*,  pathology*
Liver Cirrhosis / pathology
Neutrophils / metabolism
Prospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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