| A time-related study by Doppler and M-mode echocardiography of hemodynamics, heart size, and AV valvular function during activity-sensing rate-responsive ventricular pacing. | |
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MedLine Citation:
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PMID: 2440000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Noninvasive Doppler and M-mode echocardiography were used to: measure stroke volume (SV), left atrial (LA) size, left ventricular end-diastolic (EDD), end-systolic dimensions (ESD), left ventricular fractional shortening (FS), and for determination of mitral and tricuspid insufficiency (MI and TI) before starting and after 1, 3, and 6 months of rate-responsive ventricular pacing (RRP). The study group consisted of 13 patients (mean age, 75 years) who could be expected to benefit from an increase in cardiac output mediated by an increment of heart rate during exercise. In VVI + activity mode (RRP), the pacemaker was programmed to a basic heart rate of 60 and a maximum heart rate of 125 bpm. The SV at rest was 71 +/- 5 before RRP, and fell to 57 +/- 4 after 3 months (p less than 0.05) and to 53 +/- 4 ml/beat after 6 months of RRP (p less than .01). The LA size and ESD were unchanged during follow-up. The EDD decreased from 6.2 +/- 0.3 to 5.4 +/- 0.2 (p less than 0.002) during the first 6 months of RRP. The FS was reduced from 33 +/- 4 to 27 +/- 3% (p less than 0.02) during the first 6 months of RRP. Four of 6 patients treated previously with a VVI pacemaker (mean duration, 9 years) had MI + TI, and 3 of the 7 patients not paced previously had MI before RRP. In the last group, 1 new patient developed MI, 1 new patient developed MI + TI, and 2 patients who had MI also developed TI within 6 months of pacing. Thus, of 13 patients, 9 (69%) had either MI or MI + TI. |
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Authors:
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S Faerestrand; O J Ohm |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 10 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1987 May |
Date Detail:
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Created Date: 1987-08-05 Completed Date: 1987-08-05 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 507-18 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Arrhythmias, Cardiac / pathology, physiopathology, therapy Atrioventricular Node / physiopathology Cardiac Pacing, Artificial* Echocardiography Female Heart Rate Heart Valves / physiopathology* Heart Ventricles Hemodynamics* Humans Male Middle Aged Myocardium / pathology* Physical Exertion Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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