Document Detail

The time course of phosphorylcreatine resynthesis during recovery of the quadriceps muscle in man.
MedLine Citation:
PMID:  1034909     Owner:  NLM     Status:  MEDLINE    
The time course of phosphorylcreatine (PC) resynthesis in the human m. quadriceps femoris was studied during recovery from exhaustive dynamic exercise and from isometric contraction sustained to fatigue. The immediate postexercise muscle PC content after either form of exercise was 15-16% of the resting muscle content. The time course of PC resynthesis during recovery was biphasic exhibiting a fast and slow recovery component. The half-time for the fast component was 21-22s but this accounted for a smaller fraction of the total PC restored during recovery from the isometric contraction than after the dynamic exercise. The half-time for the slow component was in each case more than 170 s. After 2 and 4 min recovery the total amount of PC resynthesized after the isometric exercise were significantly lower than from the dynamic exercise. Occlusion of the circulation of the quadriceps completely abolished the resynthesis of PC. Restoration of resynthesis occurred only after release of occlusion.
R C Harris; R H Edwards; E Hultman; L O Nordesjö; B Nylind; K Sahlin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  367     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-04-01     Completed Date:  1977-04-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM; S    
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MeSH Terms
Adenosine Triphosphate / metabolism
Isometric Contraction
Muscles / blood supply,  metabolism*
Phosphocreatine / biosynthesis*
Physical Exertion*
Time Factors
Reg. No./Substance:
56-65-5/Adenosine Triphosphate; 67-07-2/Phosphocreatine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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