Document Detail


The time course of peritoneal transport parameters in peritoneal dialysis patients who develop encapsulating peritoneal sclerosis.
MedLine Citation:
PMID:  20566569     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Encapsulating peritoneal sclerosis (EPS) is a severe complication of peritoneal dialysis (PD). The first aim was to analyse the risk of EPS in patients who had developed ultrafiltration failure (UFF). The second aim was to identify specific peritoneal transport alterations that distinguish patients with UFF from patients who will develop EPS.
METHODS: All patients of this study were treated with PD between July 1995 and December 2008 in the Academic Medical Center, Amsterdam, the Netherlands. Risk analysis: all PD patients who developed UFF after at least 2 years of PD. Peritoneal transport analysis: all patients who had PD for at least 55 months were included: 12 EPS patients, 21 patients with UFF and 26 patients with normal ultrafiltration (UF). The peritoneal function was measured yearly with a standard peritoneal permeability analysis. UFF was defined as net UF < 400 mL after a 4-h dwell with a 3.86% dialysis solution.
RESULTS: Risk analysis: Of the 48 UFF patients, 10 eventually developed EPS. Fifty percent of the patients who continued PD for more than 3 years after the establishment of UFF developed EPS. Peritoneal function analysis: No differences were present for the time courses of solute transport and fluid transport between the EPS and the UFF groups. Overall, the EPS and normal UF groups had lower values for the effective lymphatic absorption rate (ELAR) than the UFF group.
CONCLUSIONS: The risk of EPS increases with continuation of PD while UFF is present. Transport characteristics are similar between EPS patients and UFF patients without this complication. A constantly low ELAR may distinguish the EPS patients from those with UFF only.
Authors:
Denise E Sampimon; Annemieke M Coester; Dirk G Struijk; Raymond T Krediet
Related Documents :
10201339 - Tranexamic acid increases peritoneal ultrafiltration volume in patients on capd.
9527029 - Autonomic function in patients on continuous ambulatory peritoneal dialysis.
1709899 - Activity of some lysosomal enzymes in peritoneal macrophages of patients with end-stage...
2176739 - Peroxidase activity in peritoneal neutrophils of patients with terminal renal failure t...
15627789 - Continuous ambulatory peritoneal dialysis in familial mediterranean fever amyloidosis p...
451869 - Continuing peritoneal lavage in high-risk peritonitis.
12759529 - 18f-fluorodeoxyglucose positron emission tomography (18f-fdg-pet) for staging and follo...
11724449 - Autonomic dysfunction in multiple sclerosis is related to disease activity and progress...
10201339 - Tranexamic acid increases peritoneal ultrafiltration volume in patients on capd.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-21
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  26     ISSN:  1460-2385     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  England    
Other Details:
Languages:  eng     Pagination:  291-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Division of Nephrology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. d.e.sampimon@amc.uva.nl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bariatric surgery and renal function: a precarious balance between benefit and harm.
Next Document:  A case of infection-associated antiproteinase-3-negative cytoplasmic antineutrophil cytoplasmic anti...