Document Detail

Is thyroidectomy in patients with Hashimoto thyroiditis more risky?
MedLine Citation:
PMID:  23043868     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Hashimoto thyroiditis (HT) is an organ-specific autoimmune disease characterized by the production of antibodies such as antithyroperoxidase, which leads to the destruction of the thyroid gland and a decrease in normal thyroid function. Thyroidectomy is performed when the patient presents with symptoms or potential neoplastic degeneration occurs; however, surgery can be difficult because of the dense inflammatory process around the thyroid gland. We hypothesized that patients with HT may have a higher rate of complications after thyroid surgery.
METHODS: We identified 1791 consecutive patients who underwent thyroidectomy from May 1994 to December 2009. Patients with HT were compared with those without HT with regard to outcomes with analysis of variance and chi-square test (SPSS, Inc).
RESULTS: Patients with HT were significantly younger and more likely to be female. There was no significant difference between the two groups in the rate of malignancy. However, patients undergoing thyroidectomy with HT had a significantly higher postoperative complication rate. Specifically, the rates of overall, transient, and permanent complications were all increased in HT patients.
CONCLUSION: Patients with HT had a higher rate of complications after thyroidectomy compared with those without HT. Therefore, careful consideration must be taken before pursuing operative treatment in patients with HT including providing adequate informed consent regarding the increased risks of surgery.
Catherine McManus; Jie Luo; Rebecca Sippel; Herbert Chen
Related Documents :
23252928 - Discrimination of female schizophrenia patients from healthy women using multiple struc...
24729268 - Urological evaluation of patients that had undergone in utero myelomeningocele closure:...
23105518 - Antral and duodenal disaccharidases in patients of duodenal ulcer and non-ulcer dyspepsia.
24098688 - Brain structural alterations in obsessive-compulsive disorder patients with autogenous ...
21219298 - Modulation of jak2 v617f allele burden dynamics by hydroxycarbamide in polycythaemia ve...
15260398 - Relapsing polychondritis in an elderly male.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-10-01
Journal Detail:
Title:  The Journal of surgical research     Volume:  178     ISSN:  1095-8673     ISO Abbreviation:  J. Surg. Res.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-12     Completed Date:  2013-02-25     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  529-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Hashimoto Disease / surgery*
Middle Aged
Postoperative Complications / epidemiology*
Thyroidectomy / adverse effects*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Does lumbar microdiscectomy affect adjacent segmental disc degeneration? A finite element study.
Next Document:  Project DyAdd: Visual attention in adult dyslexia and ADHD.