Document Detail

A thrice weekly in-center nocturnal hemodialysis program.
MedLine Citation:
PMID:  17603977     Owner:  NLM     Status:  MEDLINE    
The mortality associated with hemodialysis (HD) remains high. Recent studies have found that a session time of 4 to 4.5 hours and an ultrafiltration rate of less than 10 cc/h/kg were each independently associated with a decreased mortality among HD patients. We started a thrice-weekly nocturnal HD program in May 2005 and have since enrolled a total of 16 patients. The Kt/V urea (2.6 +/- 0.65 vs. 1.2 +/- 0.16, mean +/- SD, P < .05) and serum phosphorus (4.4 +/- 1.1 v 5.3 +/-1.3 mg/dL, P =.049) values obtained 6 months after enrollment in the nocturnal HD program were significantly better than the baseline values obtained before the initiation of the nocturnal HD program. The ultrafiltration rate was 5.9 +/- 1.7 mL/h/kg 6 months after patients participated in the nocturnal HD program, whereas the rates for these same patients at baseline was 10.3 +/- 4.5 mL/h/kg. Psychosocial assessments were performed at baseline and again at 6 months. No difference was seen in the results of these assessments. We conclude that patients receiving long, in-center thrice-weekly nocturnal HD have a decrease in serum phosphate, an improvement in urea clearance, and a reduction in ultrafiltration rate to less than 10 mL/h/kg. This therapy appears to have no negative impacts on a variety of quality of life measures.
Laura Troidle; Mark Hotchkiss; Fredric Finkelstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in chronic kidney disease     Volume:  14     ISSN:  1548-5609     ISO Abbreviation:  -     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-02     Completed Date:  2007-08-23     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  101209214     Medline TA:  Adv Chronic Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  244-8     Citation Subset:  IM    
Milford Hemodialysis Center, Renal Research Institute, Milford, CT, USA.
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MeSH Terms
Appointments and Schedules
Cohort Studies
Evaluation Studies as Topic
Follow-Up Studies
Hemodialysis Units, Hospital*
Kidney Failure, Chronic / diagnosis,  mortality,  therapy*
Middle Aged
Night Care / methods*
Quality of Life*
Renal Dialysis / methods*,  mortality
Risk Factors
Survival Analysis
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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