Document Detail


A three-dimensional model of the human airway tree.
MedLine Citation:
PMID:  10601169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A three-dimensional (3D) model of the human airway tree is proposed using a deterministic algorithm that can generate a branching duct system in an organ. The algorithm is based on two principles: 1) the amount of fluid delivery through a branch is proportional to the volume of the region it supplies; and 2) the terminal branches are arranged homogeneously within the organ. These principles define the basic process of branching: generation of the dimensions and directionality of two daughter branches is governed by the properties of the parent branch and the region the parent supplies. The algorithm is composed of nine basic rules and four complementary rules. When the contour of an organ and the position of the trunk are specified, branches are successively generated by the algorithm. Applied to the human lung, the algorithm generates an airway tree that consists of approximately 54,000 branches. Its morphometric characteristics are in good agreement with those reported in the literature. The algorithm and the 3D airway model are useful for studying the structure-function relationship in the lung.
Authors:
H Kitaoka; R Takaki; B Suki
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  87     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-03     Completed Date:  2000-02-03     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2207-17     Citation Subset:  IM    
Affiliation:
Department of Engineering, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan. kitaokah@image.med.osaka-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Algorithms
Bronchi / anatomy & histology*
Computer Simulation
Humans
Models, Biological*
Trachea / anatomy & histology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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