Document Detail


A three-dimensional cerebrovascular flow phantom.
MedLine Citation:
PMID:  10501059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have constructed a life-sized fully three-dimensional (3D) rigid flow-through model of the cerebral vasculature. Average vessel diameters and lengths, taken from published values in the literature, were used to describe the geometry of our phantom; numerically controlled machining techniques were used to fabricate the model. Inflow to the phantom is provided through two internal carotid arteries and two vertebral arteries. Outflow is provided through the anterior cerebral arteries, the middle cerebral arteries, and the posterior cerebral arteries. The phantom includes the circle of Willis, and aneurysms of variable size may be attached at different locations. We have tested the model for geometric accuracy using high-resolution MR and CT imaging protocols, and have found that measured and prescribed diameters agree to within better than 4%. Flow dynamics, including waveform shape and flow division between branches, also mimic that seen in vivo, with flows within 16% (on average) of the prescribed values. We present 3D magnetic resonance angiography, digital subtraction angiography, and computed rotational angiography images of the phantom under conditions that mimic physiological situations.
Authors:
R Fahrig; H Nikolov; A J Fox; D W Holdsworth
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical physics     Volume:  26     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-11-22     Completed Date:  1999-11-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1589-99     Citation Subset:  IM    
Affiliation:
Department of Medical Biophysics, University of Western Ontario, London Health Sciences Centre and The J. P. Robarts Research Institute, Canada.
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MeSH Terms
Descriptor/Qualifier:
Angiography, Digital Subtraction
Biophysical Phenomena
Biophysics
Cerebrovascular Circulation*
Evaluation Studies as Topic
Humans
Intracranial Aneurysm / pathology,  physiopathology
Magnetic Resonance Angiography
Models, Cardiovascular*
Phantoms, Imaging*
Pulsatile Flow
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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