Document Detail


A three-dimensional cerebrovascular flow phantom.
MedLine Citation:
PMID:  10501059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have constructed a life-sized fully three-dimensional (3D) rigid flow-through model of the cerebral vasculature. Average vessel diameters and lengths, taken from published values in the literature, were used to describe the geometry of our phantom; numerically controlled machining techniques were used to fabricate the model. Inflow to the phantom is provided through two internal carotid arteries and two vertebral arteries. Outflow is provided through the anterior cerebral arteries, the middle cerebral arteries, and the posterior cerebral arteries. The phantom includes the circle of Willis, and aneurysms of variable size may be attached at different locations. We have tested the model for geometric accuracy using high-resolution MR and CT imaging protocols, and have found that measured and prescribed diameters agree to within better than 4%. Flow dynamics, including waveform shape and flow division between branches, also mimic that seen in vivo, with flows within 16% (on average) of the prescribed values. We present 3D magnetic resonance angiography, digital subtraction angiography, and computed rotational angiography images of the phantom under conditions that mimic physiological situations.
Authors:
R Fahrig; H Nikolov; A J Fox; D W Holdsworth
Related Documents :
8009409 - Percutaneous transluminal angioplasty for acute stroke due to stenosis of major cerebra...
3603599 - Distribution of the occipital branches of the posterior cerebral artery. correlation wi...
8440079 - Distribution of thrombotic lesions in the cerebral arteries in spontaneous occlusion of...
7373349 - Experimental carbon monoxide leucoencephalopathy in the cat.
6400429 - Effects of barbiturates, phencyclidine, ketamine and analogs on cerebral circulation an...
1598079 - Microsurgery as an aid to middle cerebral artery endarterectomy.
11192389 - Maximal wall shear stress in arterial stenoses: application to the internal carotid art...
2139899 - Venous flow in the great cardiac vein of the dog.
22893319 - Isolated aneurysm of the proximal right subclavian artery treated with consideration to...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical physics     Volume:  26     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-11-22     Completed Date:  1999-11-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1589-99     Citation Subset:  IM    
Affiliation:
Department of Medical Biophysics, University of Western Ontario, London Health Sciences Centre and The J. P. Robarts Research Institute, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Angiography, Digital Subtraction
Biophysical Phenomena
Biophysics
Cerebrovascular Circulation*
Evaluation Studies as Topic
Humans
Intracranial Aneurysm / pathology,  physiopathology
Magnetic Resonance Angiography
Models, Cardiovascular*
Phantoms, Imaging*
Pulsatile Flow
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Quantitative pulmonary single photon emission computed tomography for radiotherapy applications.
Next Document:  A computer simulation of wavelet noise reduction in computed tomography.