Document Detail


A three-dimensional analysis of flow in the pivot regions of an ATS bileaflet valve.
MedLine Citation:
PMID:  10612303     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bileaflet heart valves are currently the most commonly implanted type of mechanical prosthetic valve, because of their low transvalvular pressure drop, centralised flow and durability. However, in common with all mechanical heart valves, implanted bileaflet valves show an inherent tendency for blood clot formation at the valve site. Fluid dynamical phenomena associated with blood clotting are elevated blood shear stresses and regions of persistent blood recirculation, particularly when both occur together. Using three-dimensional CFD modelling, combined with enlarged scale experimental modelling, we investigated the blood flow through the ATS bileaflet valve during forward flow, with particular attention to the leaflet pivot regions. Recirculating regions were found both within and downstream of the valve housing ring. Qualitative assessment of the entire cardiac cycle suggested that recirculating blood within the housing ring will be washed away whilst the valve is closed, but as with all bileaflet valve designs recirculating blood downstream of the valve may have a residence time much longer than one cardiac cycle.
Authors:
S G Kelly; P R Verdonck; J A Vierendeels; K Riemslagh; E Dick; G G Van Nooten
Related Documents :
16607913 - Flow-dependent re-endothelialization of tissue-engineered heart valves.
1550483 - Effect of venous valves on grafts for coronary artery bypass.
11711763 - Stabilization of blood homocysteine in an epidemiological setting.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  22     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-01-27     Completed Date:  2000-01-27     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  754-63     Citation Subset:  IM    
Affiliation:
Bioengineering Unit, University of Strathclyde, Wolfson Centre, Glasgow, United Kingdom. sgdkelly@wsatkins.co.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Heart Valve Prosthesis*
Models, Theoretical
Prosthesis Design
Pulsatile Flow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Oxygenation and lung morphology in a rabbit pediatric ARDS- model under high peak pressure ventilati...
Next Document:  Influence of different assist devices on survival after orthotopic heart transplantation.