Document Detail

A third case of cardiac neoplasm in a fetus with Beckwith-Wiedemann syndrome: epicardial angiofibroma.
MedLine Citation:
PMID:  15608459     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: A personal observation of a 20-week-old fetus with Beckwith-Wiedemann syndrome (BWS) presenting epicardial angiofibroma prompted us to evaluate cardiac neoplasms in this genetic condition. METHOD: We performed an autopsy and a histological evaluation of the fetus, and searched the literature for cardiac anomalies in BWS. RESULTS: Although cardiac tumors are exceptional and although BWS is rare, we found two other cardiac neoplasms in infants with BWS, whereas no more than one was expected. CONCLUSION: Besides an excess of cardiac malformation, BWS seems to favor an excess of cardiac tumors, which may occur very early.
Daniel Satgé; Evelyne Vidalo; François Desfarges; Bernard de Geeter
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  20     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2004-12-20     Completed Date:  2005-04-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  44-7     Citation Subset:  IM    
Laboratoire d'Anatomie Pathologique Centre Hospitalier, Tulle, France.
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MeSH Terms
Angiofibroma / etiology*,  pathology
Beckwith-Wiedemann Syndrome / complications*
Fetal Diseases*
Hamartoma / etiology,  pathology
Heart Diseases / etiology,  pathology
Heart Neoplasms / etiology*,  pathology
Pregnancy Trimester, First

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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