Document Detail


The thickness of the glomerular basement membrane in congenital nephrotic syndrome of the Finnish type.
MedLine Citation:
PMID:  6855995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electron microscopic examination was carried out on 10 glomeruli from 4 infants with congenital nephrotic syndrome of the Finnish type (CNF) and 5 glomeruli from 1 control. The thickness of the peripheral glomerular basement membrane (GBM) and lamina densa were measured. The width of the GBM was thinner in CNF than in the control but still within normal limits for the age and the width of the lamina densa was thinner in CNF compared to the control. This study supports earlier findings that the basic defect in CNF could be a faulty synthesis of the lamina densa.
Authors:
H Autio-Harmainen; J Rapola
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nephron     Volume:  34     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1983  
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  48-50     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Basement Membrane / pathology
Biopsy
Finland
Humans
Infant
Kidney Glomerulus / pathology*
Microscopy, Electron
Nephrotic Syndrome / congenital*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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