| Is there something special about palmitoleate? | |
| | |
MedLine Citation:
|
PMID: 23324899 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE OF REVIEW: The fatty acid, palmitoleate (16:1 n - 7), has received a lot of attention in recent years for being 'lipokine' and for the first time, we review the evidence to determine if there is something special about palmitoleate in humans. RECENT FINDINGS: Despite dietary intakes being low (<4% of total energy) palmitoleate is the second most abundant monounsaturated fatty acid in most, but not all, blood lipid pools and notably more abundant in adipose tissue. Thus, compared with other fatty acids, the palmitoleate content of lipid pools must be influenced by endogenous synthesis, which appears to be tissue and depot specific. We present a summary of dietary intervention studies of food components enriched in palmitoleate but this gives inconclusive results in regards to an impact on human metabolic regulation. SUMMARY: To date, there is no strong evidence from human studies suggesting that palmitoleate has 'lipokine' effects. However, unlike other fatty acids, there is a clear tendency towards compartmentalization and tissue-specific formation of palmitoleate, which is intriguing and requires further investigation. |
| | |
Authors:
|
Leanne Hodson; Fredrik Karpe |
Related Documents
:
|
22339649 - Influence of positional isomers on the macroscale and nanoscale architectures of aggreg... 18970689 - Determination of carbofuran in water by homogeneous immunoassay using selectively conju... 23121959 - Evaluation of pretreatment methods for enzymatic saccharification of wheat straw for bi... 16173589 - Visible light cr(vi) reduction and organic chemical oxidation by tio2 photocatalysis. 23642459 - Biodiesel from dewatered wastewater sludge: a two-step process for a more advantageous ... 18963849 - Separation of iron-52 from chromium cyclotron targets on the 2% cross-linked anion-exch... 22403579 - Microbial ch(4) and n(2)o consumption in acidic wetlands. 9630379 - Monounsaturated oils do not all have the same effect on plasma cholesterol. 17012719 - A two-year clinical evaluation of pit and fissure sealants placed with and without air ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-14 |
Journal Detail:
|
Title: Current opinion in clinical nutrition and metabolic care Volume: - ISSN: 1473-6519 ISO Abbreviation: Curr Opin Clin Nutr Metab Care Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9804399 Medline TA: Curr Opin Clin Nutr Metab Care Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
aOxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital bNational Institute for Health Research, Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Using a cervical spine cage to reconstruct malunited fibular fractures.
Next Document: Are prospective cohort studies an appropriate tool to answer clinical nutrition questions?