Document Detail

Is there seasonal variation in risk of Parkinson's disease?
MedLine Citation:
PMID:  17486603     Owner:  NLM     Status:  MEDLINE    
Recent studies suggest that, for many adult-onset neurological diseases, persons born at a certain time of year are at higher risk of the disease. Small-scale studies have suggested that persons born in the spring may be at higher risk of developing Parkinson's disease (PD) late in life. There have also been suggestions that there are clusters of PD birth dates in the years of major influenza pandemics. To determine whether there is any seasonal variation in the birth dates of PD patients, we examined birth dates of 8,168 PD patients collected from subspecialty movement disorder clinics across Canada. Patterns of seasonality of birth were examined and compared with the general Canadian population. In addition, we compared counts of patients born in the years of major influenza pandemics with the number born in the surrounding years. We found no evidence of systematic seasonal variation in PD incidence by birth date, or of clustering of birth dates during influenza pandemic years in PD patients.
Ronald B Postuma; Christina Wolfson; Ali Rajput; A Jon Stoessl; W R Wayne Martin; Oksana Suchowersky; Sylvain Chouinard; Michel Panisset; Mandar S Jog; David A Grimes; Connie Marras; Anthony E Lang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  22     ISSN:  0885-3185     ISO Abbreviation:  Mov. Disord.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-07-30     Completed Date:  2007-09-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1097-101     Citation Subset:  IM    
Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada.
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MeSH Terms
Canada / epidemiology
Cohort Studies
Disease Outbreaks
Influenza, Human / epidemiology
Parkinson Disease / diagnosis,  epidemiology*,  psychology*
Risk Factors
Seasonal Affective Disorder / diagnosis,  epidemiology*,  psychology
Severity of Illness Index

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