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Is there a role for remote ischaemic postconditioning in cardiopulmonary resuscitation?
MedLine Citation:
PMID:  20800330     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Cardiac arrest causes whole body ischaemic injury and cellular death. Successful cardiopulmonary resuscitation (CPR) can subsequently lead to a global reperfusion phenomenon with a paradoxically increased rate of cellular death. Interventions that decrease the ischaemia-reperfusion injury may be useful in the treatment of these patients. Remote ischaemic postconditioning with transient limb ischaemia is feasible in cardiac arrest patients. This article discusses the concept of ischaemic pre- and postconditioning and its potential use in patients during CPR and after return of a spontaneous circulation.
Authors:
Ronelle Mouton; Benjamin S Abella; Jasmeet Soar
Publication Detail:
Type:  Journal Article     Date:  2010-08-30
Journal Detail:
Title:  Resuscitation     Volume:  81     ISSN:  1873-1570     ISO Abbreviation:  Resuscitation     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1476-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Anaesthesia, Southmead Hospital, North Bristol NHS Trust, Bristol, BS10 5NB, UK. Ronelle.Mouton@nbt.nhs.uk
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