Document Detail

Is there a role for the incretin system in blood pressure regulation?
MedLine Citation:
PMID:  24470204     Owner:  NLM     Status:  In-Data-Review    
Incretin-based therapies are now well established for diabetes management and are among the frontline agents for control of hyperglycemia. In addition to their antihyperglycemic effects, evidence is emerging on the role of these agents on blood pressure regulation, cardioprotective and renoprotective properties. Because of the pleiotropic nature of these affects, these agents could offer significant benefits with regards to the cardiorenal metabolic complications that are part of the diabetes and obesity epidemic in the United States and worldwide. We review the various known mechanisms or pathways by which incretin based therapy exerts its regulation of blood pressure with emphasis on novel mechanisms such as inflammation/immunomodulation and oxidative stress.
Akhilesh Rao; Ravi Nistala
Related Documents :
9659654 - Response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn: r...
9189964 - Global tissue oxygenation during normovolaemic haemodilution in young children.
3728674 - Relations among canine intestinal motility, blood flow, and oxygenation.
7633704 - Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hy...
3084274 - Angiotensin ii, aldosterone and arginine vasopressin in plasma in congestive heart fail...
6723084 - Abnormalities of vascular wall sodium content in dogs with benign and malignant renal h...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current hypertension reports     Volume:  16     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-01-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Delineation of EFTUD2 Haploinsufficiency-Related Phenotypes Through a Series of 36 Patients.
Next Document:  Identification of risk factors for elevated transaminases in methotrexate users through an electroni...