| Is there a relationship between early statin compliance and a reduction in healthcare utilization? | |
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MedLine Citation:
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PMID: 20560689 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate whether compliance during the first 2 years of statin therapy is associated with reduced hospitalization rates and direct medical costs during year 3. STUDY DESIGN: An integrated pharmacy and medical claims database was used to identify adult patients with a new statin prescription between July 1, 2001, and June 30, 2002. The study tracked statin prescription refills during the first 2 years after the initial statin claim and tracked hospitalizations and direct medical costs during the first 3 years. METHODS: Patients were stratified according to compliance in the first 2 years using the medication possession ratio, where 80% or higher is compliant and less than 80% is noncompliant. The relationship between compliance rates and direct medical costs was evaluated using a generalized linear model. Adjusting for covariates that may affect cardiovascular risk, the relationship between compliance and the likelihood of hospitalization was assessed using logistic regression models. RESULTS: The 2-year medication possession ratio was 80% or higher in 3512 patients (compliant) and was less than 80% in 6715 patients (noncompliant). Compared with the noncompliant patients, the compliant patients during year 3 had significantly fewer hospitalizations (16% vs 19%) and lower total direct medical costs (excluding the cost of statin therapy) ($4040 vs $4908 per patient) (P <.01 for both). CONCLUSION: Compliance with statin therapy in the first 2 years of use may reduce hospitalization rates and direct medical costs in the subsequent year. |
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Authors:
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Ronald E Aubert; Jianying Yao; Fang Xia; Susan B Garavaglia |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of managed care Volume: 16 ISSN: 1936-2692 ISO Abbreviation: Am J Manag Care Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-21 Completed Date: 2010-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9613960 Medline TA: Am J Manag Care Country: United States |
Other Details:
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Languages: eng Pagination: 459-66 Citation Subset: H |
Affiliation:
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Medco Health Solutions, Inc, Franklin Lakes, NJ 07417, USA. ronald_aubert@medco.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Analysis of Variance Cardiovascular Diseases / prevention & control Direct Service Costs / statistics & numerical data* Drug Prescriptions / statistics & numerical data Female Health Services Research Hospitalization / statistics & numerical data* Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use* Insurance Claim Reporting / statistics & numerical data Linear Models Logistic Models Male Medication Adherence / statistics & numerical data* Middle Aged New Jersey Outcome Assessment (Health Care) Retrospective Studies Risk Reduction Behavior |
| Chemical | |
Reg. No./Substance:
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0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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