| Is there a relationship between admission blood glucose level following acute poisoning and clinical outcome? | |
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MedLine Citation:
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PMID: 22291737 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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INTRODUCTION: The aim of this study was to investigate the relationship between the admission blood glucose level following acute poisoning, severity of acute poisoning and clinical outcome. MATERIAL AND METHODS: This prospective study was conducted on 345 deliberate self-poisoning patients. Standard demographic and clinical information; admission blood glucose level; poisoning severity score and outcome were recorded. Patients with a history of diabetes mellitus, receipt of pre-sampling intravenous dextrose solution or glucocorticoids, and poisoning with toxic agents which produce hyper- or hypoglycaemia were excluded. RESULTS: Mean age of the patients was 27.5 ±8.6 years. Females outnumbered males (57.9%). Oral ingestion of more than one drug (46.7%) and opiates (14.2%) were the main causes of poisoning. Blood glucose values ranged from 50 mg/dl to 396 mg/dl. Hyper- and hypoglycaemia were observed in 23.8% and 13.91% respectively. A total of 24.41% and 22.92% of the patients in hyper- and hypoglycaemic groups had grade 3 and 4 severity score in comparison with 4.18% in the normoglycaemic group. Development of complications and death were 14.64% and 10.42% in patients with hyper- and hypoglycaemia versus 3.73% in patients with normoglycaemia. A significant difference between normoglycaemic and hyperglycaemic patients in the severity of poisoning and clinical outcome was observed (P < 0.001). CONCLUSIONS: Admission blood glucose levels may have a relationship with the severity of poisoning and clinical outcome following acute poisoning. |
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Authors:
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Ali Mohammad Sabzghabaee; Nastaran Eizadi-Mood; Farzad Gheshlaghi; Nooshin Adib; Leila Safaeian |
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Publication Detail:
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Type: Journal Article Date: 2011-03-08 |
Journal Detail:
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Title: Archives of medical science : AMS Volume: 7 ISSN: 1896-9151 ISO Abbreviation: Arch Med Sci Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2012-01-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101258257 Medline TA: Arch Med Sci Country: Poland |
Other Details:
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Languages: eng Pagination: 81-6 Citation Subset: - |
Affiliation:
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Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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