Document Detail

Is there increased monozygotic twinning after assisted reproductive technology?
MedLine Citation:
PMID:  16171467     Owner:  NLM     Status:  MEDLINE    
Over the past two decades there has been an association between assisted reproductive technologies and increased monozygotic twinning. The association is not clear nor are the causes of assisted reproductive technology-related monozygotic twinning understood, although there are several theories as to the possible mechanisms involved. This review looks at some of the assisted reproductive technologies which may be associated with an increased risk of monozygotic twinning such as intracytoplasmic sperm injection, assisted hatching and blastocyst transfers. Determining the true incidence of monozygotic twinning after assisted reproductive technologies is important as there is a well-documented increase in perinatal morbidity and mortality of monozygotic twins compared to singleton and dizygotic pregnancies.
Manuela G Toledo
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  45     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-20     Completed Date:  2006-01-27     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  360-4     Citation Subset:  IM    
Reproductive Services, Melbourne IVF, The Royal Women's Hospital, Melbourne, Australia.
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MeSH Terms
Australia / epidemiology
Embryo Transfer / adverse effects
Fertilization in Vitro / adverse effects,  methods
Infertility, Female / epidemiology,  therapy
Pregnancy, Multiple / statistics & numerical data*
Reproductive Techniques, Assisted / adverse effects*
Risk Assessment
Sperm Injections, Intracytoplasmic / adverse effects,  methods
Twins, Monozygotic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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