Document Detail


Is there a fragile(X) negative Martin-Bell syndrome?
MedLine Citation:
PMID:  3052069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During the course of the preventative screening program for the fra(X) syndrome, we identified 32 men with the phenotype but who were fra(X) negative. These were reviewed and none fitted the full criteria, so we were unable to confirm the existence of the fra(X) negative Martin-Bell syndrome. The literature and 4 families previously thought to have the fra(X) negative Martin-Bell syndrome were also reviewed. We were unable to make a concrete diagnosis of the fra(X) negative Martin-Bell syndrome.
Authors:
A Thode; S Laing; M W Partington; G Turner
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of medical genetics     Volume:  30     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:    1988 May-Jun
Date Detail:
Created Date:  1988-11-08     Completed Date:  1988-11-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  459-71     Citation Subset:  IM    
Affiliation:
Department of Medical Genetics, Prince of Wales Children's Hospital, Randwick, New South Wales, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Fragile X Syndrome / diagnosis,  genetics*
Humans
Linkage (Genetics)
Male
Mental Retardation / genetics
Middle Aged
Pedigree
Phenotype
Sex Chromosome Aberrations / genetics*
X Chromosome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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