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Is there a correlation between birth weights and first trimester crown-rump length growth velocity?
MedLine Citation:
PMID:  22468844     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: To test the hypothesis that small or large for gestational age (SGA or LGA) newborns have anomalous crown rump length (CRL) growth rates in the 1(st) trimester. Methods: Prospective observational study. Women in the 1(st) trimester presenting to the Early Pregnancy Unit, between November 2006 and December 2010, underwent transvaginal scan. Women with viable singleton pregnancies in the 1(st) trimester who had at least two CRL measurements > 5 mm, recorded at least 2 weeks apart, and also had birth weight data available were included in the final analysis. Birth weight percentiles were calculated and adjusted for gestational age and gender. SGA was equivalent to < 10(th) centile and LGA was equivalent to > 90(th) centile. Correlation analysis was performed between birthweight percentiles and first trimester CRL growth rate coefficients. Additionally, we estimated early fetal growth rates (EFGR) by calculating the Δ CRL/Δ time (mm/day) to see if these differed according to the birth weight percentiles. Results: A total of 107 women had complete data. The mean maternal characteristics were: age 27.5 +/- 6 years, weight 87 +/- 29 kg and height 163cm +/- 8 cm. The mean birth weight and gestational age at delivery were 3405 g (SD 597) and 269 days (SD 13), respectively. The proportions of SGA and LGA were 7.5% and 18.7%, respectively. There were no significant correlations between birth weight percentiles and any of the CRL growth rates. There were also no significant differences in the mean CRL velocities when comparing the SGA and LGA newborns birth weights. EFGR for SGA and LGA newborns were 1.34 (SD 0.17) mm/day and 1.32 (SD 0.24) mm/day, respectively (p>0.05). Conclusions: Newborns who are found to be SGA or LGA at delivery do not appear to have anomalous CRL growth patterns in the first trimester. The EFGR also did not correlate with birth weight percentiles.
Authors:
M Mongelli; S Reid; K Sankaralingam; N Stamatopoulos; G Condous
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-3
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Nepean Hospital, Women and Childrens' Health, PO Box 792, Penrith, Penrith, 2751 Australia.
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