| Is there an HLA antigen association with duodenal ulcer? | |
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MedLine Citation:
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PMID: 7166208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the influence of ethnic origin on the incidence of HLA antigens in duodenal ulcer, we typed 160 white Australian patients (including 22 born in Greece or Italy) and 320 blood donor controls for the HLA-A and -B loci. 5 of the 22 (22.7%) southern European patients, but only 19 of the 138 (13.8%) of the remaining duodenal ulcer patients were found to have antigen B5 compared with 27 (8.4%) of the controls. HLA-B12 was found in 55 (34.4%) duodenal ulcer patients (including 6 of the 22 southern European patients) and 117 (36.6%) controls. No significant association of duodenal ulcer with HLA-B5 or HLA-B12 was found when differences in racial origin of patients were taken into account. |
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Authors:
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D J Hetzel; B W Gabb; G D Bennett; J Hay; D J Shearman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Digestion Volume: 25 ISSN: 0012-2823 ISO Abbreviation: Digestion Publication Date: 1982 |
Date Detail:
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Created Date: 1983-05-27 Completed Date: 1983-05-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0150472 Medline TA: Digestion Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 253-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Australia Duodenal Ulcer / epidemiology, genetics, immunology* Greece / ethnology HLA Antigens / analysis* Humans Italy / ethnology Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/HLA Antigens |
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