Document Detail


A therapy inactivating the tumor angiogenic factors.
MedLine Citation:
PMID:  23311368     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This paper is devoted to a nonlinear system of partial differential equations modeling the effect of an anti-angiogenic therapy based on an agent that binds to the tumor angiogenic factors. The main feature of the model under consideration is a nonlinear flux production of tumor angiogenic factors at the boundary of the tumor. It is proved the global existence for the nonlinear system and the effect in the large time behavior of the system for high doses of the therapeutic agent.
Authors:
Cristian Morales-Rodrigo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mathematical biosciences and engineering : MBE     Volume:  10     ISSN:  1551-0018     ISO Abbreviation:  Math Biosci Eng     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101197794     Medline TA:  Math Biosci Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  185-98     Citation Subset:  IM    
Affiliation:
Departamento de Ecuaciones Diferenciales y Analisis Numerico, Facultad de Matematicas, Universidad de Sevilla, Calle Tar a s/n, 41012-Seville, Spain. cristianm@us.es.
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