Document Detail

The therapeutic significance of pulse reverse osmosis.
MedLine Citation:
PMID:  8841848     Owner:  NLM     Status:  MEDLINE    
Pulse reverse osmosis (1) is a new theory of fluid balance and exchange which suggests that the mean blood pressure and osmotic gradient control fluid balance and that the pulse controls fluid exchange. In vitro testing has confirmed some of the physico chemical principles underlying the theory (2). The hypothesis suggests a relationship between mean capillary blood pressure and osmotic gradient. Imbalance in this relationship can be related to the development of hypertension, hypotension, oedema and shock. In an attempt to test this concept mean blood pressures and colloid osmotic pressures were measured and compared in a group of 50 healthy human volunteers. The results suggest a curvilinear correlation between the mean blood pressure and the COP.
F G Prior; V Morecroft; T Gourlay; K M Taylor
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  19     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-12-12     Completed Date:  1996-12-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  487-92     Citation Subset:  IM    
Osmosis Unit, Eastern General Hospital, Edinburgh, UK.
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MeSH Terms
Blood Pressure / physiology*
Body Fluids
Capillary Permeability / physiology
Heart Diseases / metabolism,  physiopathology
Hypertension / metabolism,  physiopathology
Osmolar Concentration
Pulsatile Flow

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