Document Detail


The therapeutic efficacy of sacroiliac joint blocks with triamcinolone acetonide in the treatment of sacroiliac joint dysfunction without spondyloarthropathy.
MedLine Citation:
PMID:  19531998     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY DESIGN: Prospective case series. OBJECTIVE: The study aimed to investigate the therapeutic efficacy of sacroiliac joint (SIJ) blocks with triamcinolone acetonide in patients with SIJ pain without spondyloarthropathy. SUMMARY OF BACKGROUND DATA: Numerous studies have demonstrated that SIJ blocks with corticosteroid/anesthetic provide long-term pain relief in seronegative spondyloarthropathy. However, only one report on SIJ dysfunction patients without spondyloarthropathy shows promising results. METHODS: We conducted a prospective observational study of patients at a University Spine Center from March 2005 to May 2006. The above mentioned SIJ blocks were performed in 150 patients, and dual SIJ blocks confirmed SIJ pain in 39 patients (26%). RESULTS: Twenty-six patients (66.7%) experienced significant pain reduction for more than 6 weeks; the overall mean duration of pain reduction in these responders was 36.8 +/- 9.9 weeks. SIJ blocks were ineffective in 13 patients (33.3%); the mean duration of pain reduction in these patients was 4.4 +/- 1.8 weeks. Univariate analysis revealed that treatment failure was significantly associated with a history of lumbar/lumbosacral fusion (P = 0.03). CONCLUSION: SIJ blocks with triamcinolone acetonide are beneficial for some patients with SIJ pain without spondyloarthropathy. The SIJ blocks showed a long-lasting efficacy in two-thirds of the patients; however, the duration of its efficacy was shorter in patients with a history of lumbar/lumbosacral fusion. These findings suggest the need for further studies.
Authors:
Po-Chou Liliang; Kang Lu; Hui-Ching Weng; Cheng-Loong Liang; Yu-Duan Tsai; Han-Jung Chen
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Spine     Volume:  34     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-06-17     Completed Date:  2009-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  896-900     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. ed100172@edah.org.tw
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anti-Inflammatory Agents / administration & dosage,  therapeutic use
Arthralgia / drug therapy*,  physiopathology
Female
Follow-Up Studies
Humans
Injections, Intra-Articular
Male
Middle Aged
Prospective Studies
Questionnaires
Sacroiliac Joint / drug effects*,  physiopathology
Spondylarthropathies / pathology,  physiopathology
Treatment Outcome
Triamcinolone Acetonide / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 76-25-5/Triamcinolone Acetonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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