Document Detail

A therapeutic approach to hyperglycaemia in the setting of acute myocardial infarction: spotlight on glucagon-like peptide 1.
MedLine Citation:
PMID:  22902834     Owner:  NLM     Status:  Publisher    
Patients with acute myocardial infarction (AMI) frequently have abnormalities of glucose metabolism and insulin resistance, both of which are associated with a poor outcome. Glucagon-like peptide 1 (GLP-1) is a naturally occurring incretin with both insulinotropic and insulinomimetic properties which not only controls glucose levels but also has potential beneficial actions on the ischaemic and failing heart. In this review we highlight the underlying pathophysiological mechanisms for the development of hyperglycaemia in AMI, speculate on the potential relationship between GLP-1 and sphingosine-1-phosphate, and review the literature on the role of GLP-1 as an important approach to treating hyperglycaemia in the setting of AMI.
Emmanuel Eroume A Egom
Related Documents :
16191124 - Understanding nonresponders of cardiac resynchronization therapy--current and future pe...
22903684 - "ischemic" st elevation in a woman with left ventricular hypertrophy.
21154784 - Sequence of changes in myocardial performance index in relation with aortic isthmus and...
20592584 - Relation of qrs shortening to cardiac output during temporary resynchronization therapy...
12027794 - Pulmonary vein isolation for chronic atrial fibrillation associated with mitral valve d...
23021544 - Overlapping cardiac programs in heart development and regeneration.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-17
Journal Detail:
Title:  Therapeutic advances in cardiovascular disease     Volume:  -     ISSN:  1753-9455     ISO Abbreviation:  Ther Adv Cardiovasc Dis     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316343     Medline TA:  Ther Adv Cardiovasc Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Hull and East Yorkshire Hospitals NHS Trust, Academic Cardiology, University of Hull, Hull, East Yorkshire, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR ...
Next Document:  NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain.