Document Detail


A theoretical and experimental study of light absorption and scattering by in vivo skin.
MedLine Citation:
PMID:  7454759     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A theoretical treatment has been developed for the optical properties of a layered structure which absorbs and scatters light. This theory predicts that the logarithm of the inverse of reflectance (LIR) of the surface should be a useful parameter for the examination of that structure. This approach has been applied to a study of skin in vivo. An instrument was constructed for use in clinical situations to measure the LIR spectrum of skin over the visible region of the spectrum (450-760 nm). The contributions to the observed spectra made by pigments and the skin structure were deduced by reference to the theoretical model. Numerical indices were used to quantify the changes in skin haemoglobin content following the application of vasoconstricting preparations. The indices also provided a means of measuring erythema and melanin pigmentation induced in the skin by exposure to ultraviolet radiation. The assessments made using this instrument were more reproducible and sensitive than judgments made by eye.
Authors:
J B Dawson; D J Barker; D J Ellis; E Grassam; J A Cotterill; G W Fisher; J W Feather
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physics in medicine and biology     Volume:  25     ISSN:  0031-9155     ISO Abbreviation:  Phys Med Biol     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1981-03-27     Completed Date:  1981-03-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  695-709     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Connective Tissue / analysis
Hemoglobins
Humans
Light*
Melanins / analysis
Models, Biological
Scattering, Radiation
Skin / anatomy & histology,  blood supply
Skin Pigmentation*
Spectrophotometry / instrumentation
Vasoconstriction
Chemical
Reg. No./Substance:
0/Hemoglobins; 0/Melanins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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