Document Detail


The thalamic ataxia syndrome.
MedLine Citation:
PMID:  8190279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We identified 10 patients with contralateral ataxia and hemisensory loss following unilateral thalamic lesions. Seven patients had ischemic infarcts, and three had hemorrhages. Hemiparesis, when present, was only a transient finding, whereas ataxia, dysmetria, dysdiadochokinesia, rebound, and hemisensory loss persisted. Two patients had cerebellar outflow tremor. Another developed a severe Déjerine-Roussy pain syndrome. Four patients had lesions of the dominant hemisphere, and two had visual field deficits. None had mutism, aphasia, or astasia. On radiographic evaluation, all patients had lesions in the mid to posterior thalamus, a localization consistent with a lesion of the dentatorubrothalamic and ascending sensory pathways into the thalamus. The thalamic ataxia syndrome has a distinct localizing value that is distinguishable from the ataxic hemiparesis syndrome. Strokes occurring in the ventral lateral and posterior nuclei of the thalamus produce the clinical picture of contralateral "cerebellar" dysfunction and sensory loss with only transient weakness.
Authors:
D H Solomon; R J Barohn; C Bazan; J Grissom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  44     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-06-20     Completed Date:  1994-06-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  810-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, University of Texas Health Science Center at San Antonio 78284-7883.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Ataxia / etiology*,  pathology,  radiography
Cerebellar Ataxia / etiology,  pathology,  radiography
Cerebellar Diseases / etiology,  pathology,  radiography
Female
Hemiplegia / etiology
Humans
Infarction / complications,  pathology,  radiography
Male
Middle Aged
Sensation Disorders / etiology
Syndrome
Thalamic Diseases / complications*,  pathology,  radiography
Comments/Corrections
Comment In:
Neurology. 1995 Mar;45(3 Pt 1):598-9   [PMID:  7898733 ]

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