Document Detail

The tell-tale tasks: a review of saccadic research in psychiatric patient populations.
MedLine Citation:
PMID:  18950927     Owner:  NLM     Status:  MEDLINE    
This review focuses on saccade research with adult psychiatric patients. It begins with an introduction of the various types of saccades and the tasks used to evoke them. The functional significance of the different types of eye movements is briefly discussed. Research findings regarding the saccadic performance of different adult psychiatric patient populations are discussed in detail, with particular emphasis on findings regarding error rates, response latencies, and any specific task parameters that might affect those variables. Findings regarding the symptom, neurocognitive, and neural correlates of saccadic performance and the functional significance of patients' saccadic deficits are also discussed. We also discuss the saccadic deficits displayed by various patient groups in terms of circuitry (e.g. cortical/basal ganglia circuits) that may be implicated in the underlying pathophysiology of several of these disorders. Future directions for research in this growing area are offered.
Diane C Gooding; Michele A Basso
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-10-23
Journal Detail:
Title:  Brain and cognition     Volume:  68     ISSN:  1090-2147     ISO Abbreviation:  Brain Cogn     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-02-03     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  8218014     Medline TA:  Brain Cogn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  371-90     Citation Subset:  IM    
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MeSH Terms
Basal Ganglia / pathology,  physiopathology
Cerebral Cortex / pathology,  physiopathology
Eye Movements / physiology
Mental Disorders / complications,  physiopathology*
Ocular Motility Disorders / etiology,  physiopathology*
Psychomotor Performance / physiology*
Reaction Time / physiology
Saccades / physiology*
Task Performance and Analysis
Grant Support
R01 EY013692/EY/NEI NIH HHS; R01 EY013692-01A1/EY/NEI NIH HHS; R03 MH061806-01/MH/NIMH NIH HHS

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