Document Detail

A technique for spot application of fibrin glue during open heart operations.
MedLine Citation:
PMID:  2463794     Owner:  NLM     Status:  MEDLINE    
Several techniques have been described for preparing and applying fibrin glue to control surgical bleeding. However, these methods tend to be cumbersome, expensive, or messy. Furthermore, commercial kits have not been approved by the Food and Drug Administration because of the potential risk of hepatitis contamination. Therefore, we have devised a modified, simpler technique that enables the precise, pinpoint application of fibrin glue. The risk of hepatitis transmission is substantially reduced by using cryoprecipitate plasma instead of fibrinogen from pooled donors. This technique is especially well suited for anastomoses of small vessels or for sealing suture holes in nonporous grafts.
R Garcia-Rinaldi; P Simmons; V Salcedo; C Howland
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  47     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-02-16     Completed Date:  1989-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-61     Citation Subset:  AIM; IM    
West Houston Medical Center, Houston Heart Institute, Texas.
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MeSH Terms
Aprotinin / administration & dosage*
Calcium Chloride / administration & dosage
Cardiac Surgical Procedures*
Catheterization / instrumentation
Drug Combinations / administration & dosage
Factor XIII / administration & dosage*
Fibrin / administration & dosage
Fibrin Tissue Adhesive
Fibrinogen / administration & dosage*
Thrombin / administration & dosage*
Tissue Adhesives / administration & dosage*
Vascular Surgical Procedures
Reg. No./Substance:
0/Drug Combinations; 0/Fibrin Tissue Adhesive; 0/Tissue Adhesives; 10043-52-4/Calcium Chloride; 9001-31-4/Fibrin; 9001-32-5/Fibrinogen; 9013-56-3/Factor XIII; 9087-70-1/Aprotinin; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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