| A technique for high-sensitivity alpha autoradiography of bronchial epithelium tissue. | |
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MedLine Citation:
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PMID: 531097 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A technique for low-level alpha-particle autoradiography of bronchial epithelium utilising the plastic track detector, CR-39, is described. This plastic is new to the field of nuclear track detection and is very sensitive to alpha-particles. The recording properties of CR-39 for alpha-particles are described in detail and the technique for autoradiography discussed. This technique includes two methods of background reduction enabling activities as low as 2 alpha-particles cm-2 to be detected. The location of the point of emission of an alpha-particle from the tissue surface can be determined to an accuracy of a few micrometers. Determination of the lower limit to the energy of individual alpha-particles is possible from measurements of their range in the plastic. Examples are given of the determination of the microdistribution of alpha-particle active nuclei in bronchial tissue including the observation of two 'hot-spots' in the epithelium sample which are attributed to the presence of small particles of uranium with its daughter products. |
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Authors:
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D L Henshaw; A P Fews; D J Webster |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: Physics in medicine and biology Volume: 24 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 1979 Nov |
Date Detail:
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Created Date: 1980-04-17 Completed Date: 1980-04-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1227-42 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alpha Particles* Autoradiography / methods Bronchi* Epithelium Female Humans Male Middle Aged Plastics Radiometry / instrumentation Smoking / complications |
| Chemical | |
Reg. No./Substance:
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0/Plastics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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