Document Detail


A technique for the exposure and detection of inhaled aerosols in poultry.
MedLine Citation:
PMID:  605068     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The respiratory activity of poultry is highly susceptible to changes in respiratory dead space volume, airstream pressure, ambient temperature, and body position. A technique has been developed which will minimize these variables; yet permit the exposure and detection of inhaled aerosols. Monodispersed latex spheres of a known size are radioactively labeled following polymerization of iodine-127 onto the surface of the spheres. The bird is anesthetized and placed in a whole-body plethysmography. The liquid dispersed latex spheres are aerosolized from a nebulizer attached to a 10 p.s.i.g. compressed air line. The particles are electrostatically neutralized and routed to a plenum at near ambient pressure. The bird breathes at will through a unidirectional mask attached to the plenum. Following exposure the bird is euthanatized, the plethysmograph calibrated and the deposition in the respiratory tract measured at each of seven sections by a collimated, scintillation detector.
Authors:
R B Hayter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Poultry science     Volume:  56     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  1977 May 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  949-52     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aerosols*
Animals
Chickens / physiology*
Male
Methods
Microspheres
Polystyrenes
Respiration*
Chemical
Reg. No./Substance:
0/Aerosols; 0/Polystyrenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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