Document Detail


The taste sensory evaluation of medicinal plants and Chinese medicines.
MedLine Citation:
PMID:  17976934     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the use of the artificial taste sensor in the evaluation of 11 medicinal plants and 10 Chinese medicines with bitter and/or astringent tastes, and to assess the possible application of the sensor in the evaluation of taste and quality control of medicinal products. Aqueous extracts of the six bitter medicinal plants could be classified into three types, and those of the five astringent medicinal plants into two types, on the basis of sensor output pattern profiles. These differences seem to derive from the different structures of the main components. In the principal component analysis of the taste sensor output of 10 Chinese medicines, a new measure developed, the 'Euclidean distance', defined as the distance between a control and the targeted substance on the principal component map. This measure offers a possibility for indicating the different tastes of Chinese medicines. Lastly, we confirmed that berberine adsorption on the surface of the artificial membrane of the taste sensor was of the Langmuir type. The berberine content in extracts of medicinal plants could be evaluated by the taste sensor, and it was shown to be possible to use the taste sensor for the quality control of medicinal plants.
Authors:
Masumi Kataoka; Emi Tokuyama; Yohko Miyanaga; Takahiro Uchida
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-09-21
Journal Detail:
Title:  International journal of pharmaceutics     Volume:  351     ISSN:  0378-5173     ISO Abbreviation:  Int J Pharm     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-11     Completed Date:  2008-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804127     Medline TA:  Int J Pharm     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  36-44     Citation Subset:  IM    
Affiliation:
School of Pharmaceutical Sciences, Mukogawa Women's University, 11-68 Koshien 9-Bancho, Nishinomiya-shi, Hyogo 663-8179, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Biosensing Techniques / methods*
Drugs, Chinese Herbal / chemistry*
Membranes, Artificial
Plant Extracts / chemistry
Plants, Medicinal / chemistry*
Principal Component Analysis / methods
Quality Control
Taste*
Chemical
Reg. No./Substance:
0/Drugs, Chinese Herbal; 0/Membranes, Artificial; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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